Other biomedical studies that do not involve human subjects or are exempt from the human subjects regulations, and, therefore, do not require IRB review:.Research on the human genome and genetic markers – for the purpose of creating new avenues for understanding disease processes and their eventual control.research on the neurological changes associated with senile dementia.research on the biochemical changes associated with AIDS.Research on specific disease processes is often needed before improved methods of prevention, diagnoses, and treatment can be developed, for example:.Records research – often used to develop and refine hypotheses.Studies defining normal childhood development so that deviations from normal can be identified.Studies comparing the functioning of a particular physiological system at different stages of development ( e.g., infancy, childhood, adolescence, adulthood, or old age).responding to such things as stress or sensory stimulation.studies of the human body while exercising, fasting, feeding, sleeping, or learning.Research on normal human functioning and development:.preventive measures ( e.g., vaccines, diet, or fluoridated toothpaste).diagnostic procedures ( e.g., CAT scans, prenatal diagnosis through amniocentesis).research on therapies ( e.g., drugs, exercise, surgical interventions, or medical devices).Studies designed to evaluate the safety, effectiveness, or usefulness of an intervention:.Most clinical trials are FDA regulated, but there are some exceptions. Most biomedical research involves clinical trials, which are phased studies using human volunteers, designed to answer safety and efficacy questions about biologics, devices, pharmaceuticals, new therapies or new ways of using known treatments. Trials are often conducted in small group initially but expanding in later stages once safety and efficacy are demonstrated.

Most biomedical research is conducted by physicians or biomedical scientists, but many studies are conducted by biologists, chemists, physicists, and other medical and scientific professionals. Biomedical research applies the principles of the physical sciences to medicine. Biomedical scientists study human physiology and the treatment or understanding of disease.

What is biomedical science